For the isolated LED, check the soldering– most likely issue. Could also be backwards or damaged– may need to be replaced.
For the colums out, there appears to be a break or scratch in the vertical wire (trace) on the back side of the pcb. You may be able to see the scratch, but in any case you can repair it by adding an extra wire (e.g., a wire lead from a resistor) across the break or between the two LED leads that are supposed to be connected.
